In my mind, Highslide is the only lightbox worth using. With so many polished features such as properly pre-loading images, dynamically re-sizing large images to fit the screen, drag-ability of images, no background fading that causes the user to lose focus on the site and more...

Highslide JS for Joomla brings the wonderful world of Highslide to a GUI, with option boxes in JCE for many of the vast array of Highslide features.

There are still improvements I'd like to see, and I've found a few options work less than perfectly (I've had to fiddle with the html to get exactly what I'm looking for) but it's a great v1, and I look forward to an update and polish in v1.1