I got JooCommerce for a client who is less than computer proficient, and they are having no trouble using it with a minimal amount of guidance. The store is simple yet effective.
The support is Excellent. You can ask for help right inside the store and Flavio usually gets back to you right away with the right answer to the question.
Compared to some of the other available stores, this is by far the easiest to use. Just a simple store that looks great. I am satisfied.